Nov 29, 2012


Epigenesis is the effect of the environment on which genes express.

The genes that express are a function of our diet and other environmental influences. In our diet they are affected by three hormones. Insulin controls the glucose level in the blood. Leptin responds to the amount of fat on our body, and Mtor responds to the amount of protein in the diet.

Natural selection is designed to select those individuals who survive to pass on the information in the genes through reproduction. Once reproduction and raising children are complete, there is no selective advantage to living longer. In humans there are two main sets of genetic expression which result from conditions of food abundance in the environment.

The first environment condition is in times of abundance when there is plenty of carbohydrate and/or protein available. The genes selected during this period favor immediate reproduction as the offspring have the best chances of survival. After reproduction there is no secretive advantage to the parent living much longer past child rearing.

The second environmental condition occurs in times of scarcity when carbohydrate is unavailable and protein is merely at a survival level. Nature then selects the genetic expression which favors repair, maintenance, and living longer, so that reproduction can take place in the future when conditions are more favorable.

Realizing this epigenetic principle allows modern man to adjust his diet to favor longevity and health. This has been well researched by Dr. Ron Rosedale and consists of a diet with very low carbs and very moderate protein (about 1 gram per kg of lean body mass). Studies by Dr. Rosedale and others have indicated that the bio markers of one following this way of eating match the bio markers of people living over 100 years. In the centenarians they just inherited that genetic expression, while eating a low carb ketogenic diet can actually result in expressions of the same genes. Research shows we now have a choice to live healthy and long lives.

May 3, 2012


Several studies were conducted showing reasons why a very low carb ketogenic diet with adequate but not excess protein facilitates the genetic expression which favors longevity and health. To understand this process it is necessary to look at the deeper mechanics which lead to health and longevity. For many years scientists have known that the hormone leptin has a strong effect on obesity. Drug companies tried to capitalize on this but found they could not just give an injection of leptin and produce weight loss. Leptin works in the body as a feedback mechanism and has to be sensitive to the intake of nutrients to regulate appetite.

No diet will work if the person is hungry. Almost all obese people actually have excess leptin. These people are leptin resistant. Leptin and insulin are the most important biochemicals in the body when it comes to health and longevity. These hormones are controlled by what one eats. Leptin is a powerful hormone which is produced by fat cells. Modern scientists realize that fat is not just inert tissue but is actually an endocrine organ like the pancreas and pituitary, influencing the body and particularly the brain. Leptin is a powerful regulator which tells the brain what to do about life’s two main biological goals: eating and reproducing.  It takes lots of fuel to make babies. Your fat, by way of leptin, provides feedback to your brain telling you whether you should be hungry, eat and make more fat. It (along with insulin) tells the brain whether the time is nutritionally ripe to make babies, or whether the body should work to maintain and repair itself to reproduce at a future when more energy is available. It is a biological intelligence system; your fat by way of leptin actually controls your brain.

Leptin is one way this intelligence is transmitted to the brain. This now starts to show the evolutionary advantage to becoming leptin sensitive. It not only takes lots of energy to make babies, it takes a lot of energy to keep you healthy. It is clear from recent research that by controlling leptin and insulin one can increase the genetic expression which favors health and longevity. In evolution by natural selection, the body developed these two major ways of dealing with nutrition one by using sugar and the other by using fat as fuel. If food was plentiful, nature favored breeding. Remember that natural selection only cares that the genes express which favor future reproduction. After reproduction nature doesn't care if we live long and prosper, but only that the genetic information is passed along. This is much like the cells in our body. If individual cells die it doesn't affect the overall health of the body which goes on. In the same way creative intelligence cares only that life goes on collectively.

In times of scarcity the genes express which favor postponing the reproduction until there is more food available. It does this by increasing the repair and longevity mechanisms of the body. It has been known for decades that by calorically restricting the nutrition of an organism, its lifespan is dramatically increased. Obviously not too many people would be interested in living this way however.

Fortunately science has now shown that it’s not necessary to restrict all calories but only certain nutrients. By reducing the amount of carbohydrates as much as possible, while providing adequate but not excessive protein and high healthy oil as needed to meet caloric needs the body begins to down regulate the markers of aging and disease. This was demonstrate in a study Clinical Experience of a Diet Designed to Reduce Aging

The markers which resulted were markers present in other studies of long lived people who were more than 100 years of age. The only thing these people had in common (some drank, smoked etc), was that they had these markers. They all had low fasting sugar levels, low fasting insulin levels, and low triglycerides. They also had a somewhat lower resting metabolism. Although many of these individuals inherited these markers the preceding study indicates that his can be reproduced by proper diet.

Dr. Ron Rosedale has created the specific diet which was used in the study and it can be eaten by meat eaters, vegetarian, or vegans. 

Recent Research

Longevity is the most global measure of health. The approaches to diet such as the introduction of trans fats and vegetable oils (except extra virgin olive oil and coconut oil) were initially thought to be healthy and reduce heart attacks, however the promoters of these foods didn't account for the increased inflammation and cancer that seems correlated with this type of oil. Overall longevity is reduced.

Recent research by Dr. Ron Rosedale, Dr. Stephen Phinney and others have clearly indicated that a nutritional ketogenic diet which is very low in carbohydrates, including only high fiber low starch vegetables, adequate protein. Adequate protein is about 1 gram per kilogram of lean body mass. This way of eating includes a large amount of healthy fat and oils, which should comprise most of the calories in the diet.

What a diet like this does is cause the body to switch from sugar burning to fat burning, which results in numerous health benefits. It takes about 3 weeks for the body to adapt to the change in fuel. A person may experience some discomfort during this period since the body has little carbohydrates and has not yet fully adapted to fat burning. Once adapted, and during the process it’s important to not cheat or eat carbohydrates since even one meal will stop the adaptation and require going through the whole process again. But longevity and great health is worth it.

In the article "Clinical Experience of a Diet Designed to Reduce Aging" (Journal of Applied Research, vol 9, no 4, 2009 Rosedale, Westman, Konhilis,, it is stated:

“This retrospective analysis of patients from a private clinic adhering to a high-fat, low carbohydrate, adequate protein diet [the Rosedale diet] demonstrated reductions in critical metabolic mediators including insulin, leptin, glucose, triglycerides, and free T3… Patients in this study demonstrated a similar directional impact on the measured parameters when compared to studies using more established models of longevity such as caloric restriction. We may have found a way to mimic caloric restriction, at least to some extent and any extent is extraordinary. It appears that my diet can mimic the hormonal changes in T3, insulin, and leptin seen in calorie restriction studies that are instrumental to mediate the major physiological and extremely beneficial effects of calorie restriction, but without having to calorie restrict. This could more rightfully be called the perfect diet."

The protein restriction, according to Dr. Rosedale, results in reduction of specific amino acids. These amino acids are naturally lower in vegetable protein than in animal protein. Combining this with a very low carb high fat vegetable diet naturally gives the best of both worlds. If the dietary fat was limited to olive oil, which has a low level of saturated fat, the body then tends to use more of its own saturated body fat creating an even healthier profile. Dr. Rosedale’s information can be found at the following link.

The Flexi Diet shows a ketogenic diet can be eaten while being completely vegetarian or vegan.

Vegan Version of the Rosedale Diet

The Rosedale Diet has great success in improving health and more importantly, increasing longevity based on science. The Flexi Diet can show a way of eating the Rosedale diet while eating vegan with no animal products while staying within the guidelines Dr. Rosedale recommends. This is a very low carb ketogenic diet with researched health benefits.

Typical vegan version:
  • Use high quality vegetable protein, which contains no carbohydrates. The best of these proteins is the Gemma Pea Isolate. Avoid soy protein as there are reported health risks.
  • Eat as much healthy oil as needed to satiate hunger. These would include extra virgin olive oil, virgin coconut oil, and nuts or nut butters. (Peanuts are not a nut).
  • With nuts and nut butter add the protein to your daily total.
  • Avoid other vegetable oils as they are too high in omega 6. To get sufficient omega 3 the best is cod liver oil, but as that’s not vegan one could use flax oil.
  • Eat fibrous vegetables as much as desired but avoid all starchy vegetables such as potatoes. Avoid all grains and other starches, as well as all sugars, syrups etc.
  • Determine you lean body mass (formulas and calculators are on line) and eat 1 gram of protein per kilogram of lean body mass.
  • People eating this way have had great health gains in all areas of their lives.


Refined Sugar

It has previously been mentioned that sugars and excess carbohydrates trigger the hormone insulin which stimulates the appetite to cause fat storage. Refined sugar can achieve this more effectively and faster than any other carbohydrate. Refined sugar is just about the 'greatest evil'. In case you may think I am joking, you may like to consider how diabetes is the 7th leading cause of death in the United States according to the National Institute of Diabetes. If you may still think that I may be exaggerating the 'evil' nature of refined extracted sugar, you may like to consider how diabetes is the leading cause of many additional complications more than any other known disease, including kidney failure, pregnancy complications, non traumatic lower-limb amputations, cases of blindness among adults in the United States, nervous system complications, dental complications and many others, along with being the number one cause of hypertension, heart disease and stroke in the nation. Furthermore, the National Institute of Diabetes estimates that in addition to the 18.8 million people officially diagnosed with diabetes, there would be around 7 million more undiagnosed diabetes sufferers in the U.S. As one may conclude from this data, the ill health of a prosperous nation like the U.S. is mainly due to refined sugar.

Refined sugar is a very unnatural extracted substance that destroys the body's entire appetite balance by going into the bloodstream too directly and rapidly, triggering huge amounts of unnatural insulin spikes, causing people to overeat excessively. As one can see, being able to overcome 'sugar addiction' with the Flexi Diet would cause your appetite to gradually normalize more. Your energy would also gradually become more even and steady without the sugar-induced heights and crashes. These innumerable benefits and the sufficient protein and healthy oils and the abundance of fresh vegetables in the diet, as we are convinced, would guarantee optimum health. It would be the key to fastest rejuvenation for people not in perfect health.



It would be almost impossible for most overweight people to be able to complete calorie restricted diets. Many people find the hunger simply too overwhelming to put up with. As most people know only too well most overweight/sugar addicted people love to eat due to high insulin levels. Sooner or later a sugar addicted person will go off a low calorie diet.

The secret to maintaining long term weight is to not experience hunger. When one eats a ketogenic diet with a Woodyatt ration of at least 2, after about three weeks or less, one no longer experiences hunger. This is because carbohydrates trigger a sudden rise in blood sugar which is followed by a spike in insulin which then lowers the blood sugar below its previous levels causing hunger. The key to avoiding hunger, eat a ketogenic diet.

Jan 3, 2012


Problems with Insufficient Protein 

I would like to discuss the primary problem with many vegetarian diets - the tendency toward insufficient protein intake. Without enough protein our skin cannot re-generate its collagen which gives it elasticity and youthfulness. The muscle tissues also rely on protein to stay developed and firm. As one ages there is a tendency to loose muscle mass. This process is known as sarcopenia. in addition to muscle mass most other organs require sufficient protein. People who do not get sufficient protein over a long enough period usually develop signs of premature aging and very poor health. You may have noticed some vegetarians looking more wrinkled up and saggy and older than the average non-vegetarian person of the same age group. This is because it can be very hard for vegetarians to get sufficient protein. Many people find vegetarian sources of protein such as legumes and beans hard to digest, making it difficult being a vegetarian. Some people resort to animal protein, or vegan and vegetarian diets tend to degenerate into diets with a high level of carbohydrates and sugar.

In addition to premature aging and ill health, in a protein deficient vegetarian diet, the excessive carbohydrates and sugars would over-stimulate the appetite to encourage overeating and snacking. This is because simple carbs and worst of all refined sugar cause appetite spikes by triggering the insulin hormone - the hormone responsible for fat storage. Thus vegetarians who eat too many simple carbohydrates may end up overweight or even obese. In the detailed information we provide about   weight loss, it is explained that unlike simple carbohydrates, protein and good oils have appetite suppressing effects due to being slower to digest, grounding and satisfying. Thus another serious diet mistake commonly made is to deprive oneself of sufficient amounts of good oils and fats. Low fat diets usually end up defeating their purpose by their inability to satisfy the hunger stimulus, leading to failure and frustration, resulting in more weight gain.